Table of Contents

• Current approaches to the management of neuroendocrine breast carcinoma (NEBC): a review

  Mohsen S. Ali

  Neuroendocrine breast carcinoma (NEBC), an infrequent malignancy, accounts for 2–5% of all invasive breast cancer cases. The minimal occurrence of these tumours has resulted in knowledge primarily acquired from unique case reports or short retrospective studies. NEBC is diagnosed by identifying morphological characteristics related to gastrointestinal tracts and lung neuroendocrine tumors and neur...

  REVIEW | Published: 27 Nov 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 85-94   PDF(2870KB)   Views：96Downloads：3

• Molecular mechanism of tumor microenvironment and recent approaches for the immunotherapy of pancreatic cancer

  Ayesha Fazal Nawaz, Muhammad Arif

  One of the most aggressive cancers, pancreatic cancer (PC) frequently has a dismal prognosis. The only known treatment for this illness is surgery, which is usually followed by adjuvant chemotherapy. However, only a tiny percentage of patients with resectable and non-metastatic tumors can receive surgery. In the future, more patients may be eligible for surgery thanks to customized neoadjuvant the...

  REVIEW | Published: 21 Dec 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 95-103   PDF(1590KB)   Views：66Downloads：2

• Next frontier in cancer treatment: an iPSC supported CAR-T cell therapies

  Tayyaba Sona

  The spread of cancer and huge number of cancer related deaths has made it imperative for scientist to search new diagnostic, prognostic and treatment tools for its effective management. Chimeric Antigen Receptor (CAR) T-cell (CAR-T) therapy has been brought into limelight as novel treatment strategy for cancer. In this review we briefly introduced the CAR-T therapy highlighting its successful app...

  REVIEW | Published: 27 Dec 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 104-111   PDF(1890KB)   Views：50Downloads：0

• Cellular senescence and tumor dormancy at the crossroads of therapy resistance, metastasis and cancer stemness

  Qurrat Ul Ain

  Senescence is irreversible cell cycle arrest that results from therapy-induced stress such as DNA damage. It was initially thought to be a tumor-suppressive mechanism, but now getting attention to contribute to tumor progression and therapy resistance through the senescence-associated secretory phenotype (SASP). Remodeling the tumor microenvironment (TME), SASP can establish conditions conducive t...

  REVIEW | Published: 29 Dec 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 112-120   PDF(1490KB)   Views：41Downloads：1