Asia-Pacific Journal of Oncology

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Table of Contents

  • Progress in research and treatment of immune checkpoints in breast cancer

    Xinyi Zhang, Jie Wang, Kaiyuan Zhou

    Breast cancer is the most common malignant tumor among women often involving the toxicity of conventional chemotherapy alongside organ-specific side effects. As immunotherapeutic agents in anti-tumor, new immune checkpoints are constantly being dug and discovered. The role of immune checkpoint inhibitors in the process of tumor immune evasion has assumed increasing significance. Currently, clinic...

    REVIEW | Published: 08 Apr 2024

    Asia-Pacific Journal of Oncology, Articles, Online First

    Pages: 9-15   PDF(626KB)   Views:144Downloads:3

  • Research progress of perioperative immunotherapy for locally advanced gastric cancer

    Shanbo Ma, Wei Zhang ... Hongbo Jiang

    Gastric cancer is a highly heterogeneous disease, and its occurrence and development are the result of genetic factors, environmental factors, and host factors. As one of the main types of cancer in China, radical gastrectomy is the only chance for patients to be cured, but only 50% to 60% of initially diagnosed gastric cancer patients are suitable for radical gastrectomy, especially in locally ad...

    REVIEW | Published: 08 Mar 2024

    Asia-Pacific Journal of Oncology, Articles, Online First

    Pages: 1-8   PDF(973KB)   Views:331Downloads:2

  • Characteristics and outcomes of patients with small cell lung cancer - findings from a New Zealand SACT database

    Ross Lawrenson, Ha Nguyen ... Ian Kennedy

    Background Small Cell Lung Cancer (SCLC) SCLC generally presents late and is treated with systemic anti-cancer treatment (SACT). Māori are over represented in Lung Cancer statistics but disparities between Māori and non-Māori in patterns of care and survival from SCLC have not been previously reported. Methods We used the custom-built SACT database collected by the Oncology Department at Waikato ...

    RESEARCH | Published: 10 Feb 2023

    Asia-Pacific Journal of Oncology, Articles, Volume 4 (2023)

    Pages: 1-9   PDF(815KB)   Views:678Downloads:1

  • Associations between KRAS status and clinical features in non-polyp colon cancer patients

    Cuong Hoang Minh, Huong Bui Thi Thu ... Thang Vu Hong

    Background Mutations of the KRAS gene are common in cancers; they are detected at a very high rate in colon cancer (CC) and are considered a negative disease factor. CC is among the deadliest cancers in Vietnam, and KRAS status for non-polyp colon cancer (NPCC) was rarely reported from the country. In this study, we aim to determine KRAS mutations and the associations of mutation status with clini...

    RESEARCH | Published: 29 Jun 2023

    Asia-Pacific Journal of Oncology, Articles, Volume 4 (2023)

    Pages: 10-16   PDF(1008KB)   Views:497Downloads:1

  • A mini-review on metal-based breakthroughs in photodynamic therapy

    S. Dhinesh Kumar, Kaaviya. J

    This work aims to present Photodynamic Therapy (PDT) as an emerging approach for combating cancer, highlighting its effective therapeutic potential and distinctive attributes. Photodynamic therapy (PDT) stands as a groundbreaking approach in cancer treatment, rooted in Tappeiner’s revelation of oxygen-dependent photosensitizers’ impact on tumor cells under light. PDT operates by leveraging specifi...

    REVIEW | Published: 02 Dec 2023

    Asia-Pacific Journal of Oncology, Articles, Volume 4 (2023)

    Pages: 17-21   PDF(500KB)   Views:292Downloads:2

  • An invitro evaluation of the cytotoxicity and p53-mediated apoptotic effect of ocimum sanctum leaves hexane extract on human oral cancer cell lines

    VR Naghul, Jerrine Joseph ... V. Ramesh Kumar

    Background Oral cancer is one of the most common cancers and the leading cause of cancer deaths worldwide. Florae have been inspiration of salutary sources for curing ailments since ages. Hence, the contemporary investigation was aimed at evaluating the anti-proliferative activity of extract of Ocimum sanctum leaves on oral cancer KB mouth cell line. Methods Extract preparation using soxhlet appa...

    RESEARCH | Published: 27 Dec 2022

    Asia-Pacific Journal of Oncology, Articles, Volume 3 (2022)

    Pages: 1-9   PDF(1680KB)   Views:682Downloads:1

  • Adverse effects of the cancer therapy on osteoclast-mediated bone loss in patients with cancers: a challenge

    Manh Tien Tran

    It is well-known that cancer therapies, including chemotherapy drugs, aromatase inhibitors and gonadotropin-releasing homone analogues, commonly contribute to remarkably reduce the bone mineral density, subsequently increase the rate of bone loss. For instance, in the patients with prostate cancer treated with androgene deprivation therapy (ADT), or chemotherapy drugs such as doxorubicin and cispl...

    REVIEW | Published: 31 Dec 2022

    Asia-Pacific Journal of Oncology, Articles, Volume 3 (2022)

    Pages: 10-15   PDF(484KB)   Views:711Downloads:1

  • Nanogold: a versatile therapeutic agent in oncology

    Mater H. Mahnashia, Bander A. Alyami ... Arif Ullah Khan

    Nanogold is an emerging and versatile therapeutic agent since decades. Nanoogold and its’complexes can be synthesized through different ways. Its’ use in oncology as a drug delivery vehicle, phothothermal agent, Nucliec acid delivery vehicle and a photodynamic agent has been investigated by many researchers. Au nanoparticles (AuNPs) are nanovehicles with inimitable optical properties and incredibl...

    REVIEW | Published: 31 Dec 2022

    Asia-Pacific Journal of Oncology, Articles, Volume 3 (2022)

    Pages: 16-21   PDF(630KB)   Views:587Downloads:1

  • Genetic modification of mesenchymal stem cells to enhance their anti-tumor efficacy

    Swathi Vangala, Gopikrishna Moku

    Non-hematopoietic mesenchymal stem cells (MSCs) are widely used in regenerative medicine and tissue engineering as they possess multilineage differentiation potential and self-renewal properties. MSCs can be easily isolated from several tissues and expanded following standard cell culture procedures. MSCs have the capability of mobilization to the tumor site; so, they can automatically relocate to...

    REVIEW | Published: 30 Mar 2021

    Asia-Pacific Journal of Oncology, Articles, Volume 2 (2021)

    Pages: 1-6   PDF(484KB)   Views:1428Downloads:2

  • Fabrication and bioactivity evaluation of curcumin and paclitaxel loaded lipid nanoparticles of pH-sensitive histidinylated cationic amphiphile

    Swathi Vangala, Gopikrishna Moku

    Drug resistance, inefficient cellular uptake and the subservient drug release to increase the intracellular drug concentration inside the tumor cells are the key reasons for low therapeutic efficacy of drug-loaded lipid nanoparticles in cancer therapy. Herein, we report on the design, synthesis and bioactivity evaluation of Curcumin & Paclitaxel (PTX) encapsulated endosomal pH-Sensitive lipid nano...

    RESEARCH | Published: 15 Apr 2021

    Asia-Pacific Journal of Oncology, Articles, Volume 2 (2021)

    Pages: 7-16   PDF(3344KB)   Views:1328Downloads:2