Table of Contents

• Current perspectives on glioblastoma treatment synergies between therapies and delivery systems

  Debanjan Das

  In adults, glioblastoma multiforme (GBM) is considered the most widespread and virulent malignancy of the central nervous system (CNS). This formidable brain tumor stands out as one of the most lethal types within the CNS cancer classification. Despite ongoing advancements in modality therapy, a curative solution remains largely unattainable. Consequently, the imperative to develop innovative syst...

  REVIEW | Published: 05 Jan 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 1-8   PDF(1050KB)   Views：1169Downloads：9

• Liquid biopsy: an emerging field with new opportunities for cancer diagnosis and prognosis

  Dhahiri Saidi Mashausi, Semukunzi Herve

  Cancer grades among the deadliest diseases, globally causing the death of a over million people each year. Early diagnosis has been considered ideal for efficient treatment as during later stages chances of treatment become limited. However, gold standard tissue biopsy has various limitation for instance, late-stage diagnosis and its intrusive operation making it unfit for repeated sampling. Scien...

  REVIEW | Published: 14 Jan 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 9-17   PDF(1990KB)   Views：982Downloads：16

• Innovative and future approaches for ovarian cancer detection and evaluation: a comprehensive review

  Fomukong Tasinda Raphael, Simon Nabirye

  Gynecological malignancies, characterized by their aggressive nature and tendency to recur, are associated with poorer outcomes and suboptimal responses to available treatment modalities. Ovarian cancer (OC) is frequently present at advanced stages, wherein therapeutic resistance, angiogenesis, recurrence, and metastatic spread significantly affect patient survival rates. The primary therapeutic a...

  REVIEW | Published: 04 Feb 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 18-26   PDF(1370KB)   Views：998Downloads：4

• Deubiquitinases as novel therapeutic targets in colorectal cancer

  Noor Al Shukri, Razik Bin Abdul Momin

  Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality and is the third most prevalent malignant tumor in the world. In recent years, the key role of protein post-translational modifications, especially ubiquitination and deubiquitination modifications, in tumorigenesis and progression has gradually been revealed. Deuubiquitinating Enzymes (DUBs) play an important role in...

  REVIEW | Published: 17 Mar 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 27-36   PDF(1563KB)   Views：810Downloads：5

• Potential mechanisms of intestinal microbes in bone metastasis of breast cancer

  Nicky Gile, Luke Johnston

  Breast cancer (BRCA) is the most common type of cancer in women worldwide, with distant metastases most frequently occurring in the skeleton. Bone metastasis in BRCA often leads to severe bone pain, pathological fractures, spinal cord compression, and other complications, significantly reducing the patients' quality of life. Recently, the role of intestinal microbes in BRCA bone metastasis has gai...

  REVIEW | Published: 31 Mar 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 37-46   PDF(2290KB)   Views：700Downloads：4

• Applications and future prospects of artificial intelligence in the diagnosis and prognosis of lung cancer

  Soha Kareem

  With its annual incidence gradually rising and hence a major threat to public health, lung carcinoma is a major contributor to cancer-associated death worldwide. Artificial intelligence (AI) in computer science refers to research on robots, language processing, image recognition, speech, and machine learning (ML) applications. This will change the physician’s approach to cancer management. Given i...

  REVIEW | Published: 15 Sep 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 47-54   PDF(1710KB)   Views：388Downloads：6

• Ubiquitin-specific proteases as emerging molecular drivers and therapeutic targets in hepatobiliary cancers

  Enas Roumieh, Waqas Bin Ismail, Samahir Sheikh Idris

  Hepatobiliary malignancies, such as gallbladder carcinoma (GBC), cholangiocarcinoma (CCA), and hepatocellular carcinoma (HCC), continue to be extremely deadly because of their late diagnosis, intertumoral heterogeneity, recurrence, and resistance to treatment. Finding new molecular drivers is crucial to enhancing diagnosis and therapy. Hepatobiliary tumor biology is significantly regulated by the ...

  REVIEW | Published: 31 Oct 2025

  Asia-Pacific Journal of Oncology, Articles, Volume 6 (2025)

  Pages: 55-69   PDF(3633KB)   Views：216Downloads：6