Table of Contents

• Liquid biopsy: an emerging field with new opportunities for cancer diagnosis and prognosis

  Dhahiri Saidi Mashausi, Semukunzi Herve

  Cancer grades among the deadliest diseases, globally causing the death of a over million people each year. Early diagnosis has been considered ideal for efficient treatment as during later stages chances of treatment become limited. However, gold standard tissue biopsy has various limitation for instance, late-stage diagnosis and its intrusive operation making it unfit for repeated sampling. Scien...

  REVIEW | Published: 14 Jan 2025

  Asia-Pacific Journal of Oncology, Articles, Online First

  Pages: 9-17   PDF(1990KB)   Views：54Downloads：5

• Current perspectives on glioblastoma treatment synergies between therapies and delivery systems

  Debanjan Das

  In adults, glioblastoma multiforme (GBM) is considered the most widespread and virulent malignancy of the central nervous system (CNS). This formidable brain tumor stands out as one of the most lethal types within the CNS cancer classification. Despite ongoing advancements in modality therapy, a curative solution remains largely unattainable. Consequently, the imperative to develop innovative syst...

  REVIEW | Published: 05 Jan 2025

  Asia-Pacific Journal of Oncology, Articles, Online First

  Pages: 1-8   PDF(1050KB)   Views：88Downloads：1

• Cellular senescence and tumor dormancy at the crossroads of therapy resistance, metastasis and cancer stemness

  Qurrat Ul Ain

  Senescence is irreversible cell cycle arrest that results from therapy-induced stress such as DNA damage. It was initially thought to be a tumor-suppressive mechanism, but now getting attention to contribute to tumor progression and therapy resistance through the senescence-associated secretory phenotype (SASP). Remodeling the tumor microenvironment (TME), SASP can establish conditions conducive t...

  REVIEW | Published: 29 Dec 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 112-120   PDF(1490KB)   Views：97Downloads：2

• Next frontier in cancer treatment: an iPSC supported CAR-T cell therapies

  Tayyaba Sona

  The spread of cancer and huge number of cancer related deaths has made it imperative for scientist to search new diagnostic, prognostic and treatment tools for its effective management. Chimeric Antigen Receptor (CAR) T-cell (CAR-T) therapy has been brought into limelight as novel treatment strategy for cancer. In this review we briefly introduced the CAR-T therapy highlighting its successful app...

  REVIEW | Published: 27 Dec 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 104-111   PDF(1890KB)   Views：97Downloads：0

• Molecular mechanism of tumor microenvironment and recent approaches for the immunotherapy of pancreatic cancer

  Ayesha Fazal Nawaz, Muhammad Arif

  One of the most aggressive cancers, pancreatic cancer (PC) frequently has a dismal prognosis. The only known treatment for this illness is surgery, which is usually followed by adjuvant chemotherapy. However, only a tiny percentage of patients with resectable and non-metastatic tumors can receive surgery. In the future, more patients may be eligible for surgery thanks to customized neoadjuvant the...

  REVIEW | Published: 21 Dec 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 95-103   PDF(1590KB)   Views：107Downloads：2

• Current approaches to the management of neuroendocrine breast carcinoma (NEBC): a review

  Mohsen S. Ali

  Neuroendocrine breast carcinoma (NEBC), an infrequent malignancy, accounts for 2–5% of all invasive breast cancer cases. The minimal occurrence of these tumours has resulted in knowledge primarily acquired from unique case reports or short retrospective studies. NEBC is diagnosed by identifying morphological characteristics related to gastrointestinal tracts and lung neuroendocrine tumors and neur...

  REVIEW | Published: 27 Nov 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 85-94   PDF(2870KB)   Views：133Downloads：4

• Breast cancer stem cells origins and the memory stem cells: clinical significance of biomarkers and the active therapeutic approaches

  Muhammad Waseem Akram, Bai Chen

  Despite recent improvements in diagnosis and treatment, breast cancer (BC) remains one of the leading causes of cancer-related deaths among women. In this complex disease, breast cancer stem cells (BCSCs) are a small but significant subset of different cancer cells with the ability to proliferate and self-renew. According to an increasing amount of studies, BCSCs are essential for breast cancer me...

  REVIEW | Published: 08 Nov 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 76-84   PDF(1430KB)   Views：161Downloads：2

• The role of miRNAs as biomarkers in cancer

  Yifan Ou, Zhen Ren

  MicroRNAs (miRNAs), a class of non-coding RNAs, play a critical role in regulating gene expression and have demonstrated significant potential as biomarkers in cancer research. This review explores the role of miRNAs in tumorigenesis, invasion, and metastasis, highlighting their altered regulation in various cancers, including lung, breast, liver, colorectal, and prostate cancer. miRNA expression ...

  REVIEW | Published: 22 Oct 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 66-75   PDF(951KB)   Views：222Downloads：2

• Research advances in tumor diagnosis and early detection

  Rodney Bradly

  This review explores recent advances in tumor diagnosis and early detection, focusing on cutting-edge developments in molecular diagnostic technologies, imaging techniques, and the integration of multi-omics data. Current tumor diagnostic methods have limitations in terms of sensitivity and specificity, particularly for early tumor detection. However, with continuous progress in research and emerg...

  REVIEW | Published: 08 Oct 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 55-65   PDF(1050KB)   Views：224Downloads：3

• Research progress on the mechanisms, assessment methods, and intervention strategies for glioma-related cognitive impairment

  Riffat Iqbal, Zeeshan Ashraf

  Glioma-related cognitive dysfunction has emerged as a significant issue that affects the quality of life of patients. This paper aims to review the latest advancements in research on the mechanisms, assessment methods, and intervention strategies for glioma-induced cognitive impairment. First, it explored the potential mechanisms underlying glioma-related cognitive dysfunction, including the influ...

  REVIEW | Published: 11 Sep 2024

  Asia-Pacific Journal of Oncology, Articles, Volume 5 (2024)

  Pages: 46-54   PDF(1010KB)   Views：297Downloads：3